Maternal Pre-conception Body Mass Index and Fasting Plasma Glucose With the Risk of Pre-term Birth: A Cohort Study Including 4.9 Million Chinese Women.

ABSTRACT: Background: To evaluate the associations of pre-conception body mass index (BMI), fasting plasma glucose (FPG) alone and their combination with pre-term birth (PTB) risk. Methods: We conducted a population-based retrospective cohort study with 4,987,129 reproductive-aged women, who participated in National Free Pre-Pregnancy Checkups Project in 2013-2016 and had a singleton delivery before December 2017 in China. All data analyses were conducted in 2018-2021. Results: A total of 339,662 (6.81%) women had pre-term deliveries. Compared with women with normal weight and normal glucose, underweight and normal weight were associated with PTB among hypoglycemia women, the adjusted odd ratios (aORs) were 1.24 (95% CI: 1.05-1.48) and 1.16 (95% CI: 1.07-1.25), respectively; und

SUBMITTER: Xu Q 

PROVIDER: S-EPMC9580732 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature