Summary Visualizations of Gene Ontology Terms With GO-Figure!

ABSTRACT: The Gene Ontology (GO) is a cornerstone of functional genomics research that drives discoveries through knowledge-informed computational analysis of biological data from large-scale assays. Key to this success is how the GO can be used to support hypotheses or conclusions about the biology or evolution of a study system by identifying annotated functions that are overrepresented in subsets of genes of interest. Graphical visualizations of such GO term enrichment results are critical to aid interpretation and avoid biases by presenting researchers with intuitive visual data summaries. Amongst current visualization tools and resources there is a lack of standalone open-source software solutions that facilitate explorations of key features of multiple lists of GO terms. To address this we dev

SUBMITTER: Reijnders MJMF 

PROVIDER: S-EPMC9581009 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature