Ontology highlight
ABSTRACT: Clinical trial registration
ClinicalTrials.gov number, NCT04666168.
SUBMITTER: Zhang W
PROVIDER: S-EPMC9581047 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Zhang Wenqi W Huang Chen C Liu Ruixia R Zhang Huichao H Li Weijing W Yin Shaoning S Wang Lianjing L Liu Wei W Liu Lihong L
Frontiers in immunology 20221005
Current therapeutic strategies for central nervous system (CNS) relapse of diffuse large B-cell lymphoma (DLBCL) are extremely limited. Secondary central nervous system lymphoma (SCNSL) also shows a grave prognosis and high mortality. This report describes a young female patient with DLBCL and CNS relapse who received low-dose CD19-directed chimeric antigen receptor T (CAR-T) cell therapy followed with Bruton's tyrosine kinase inhibitor and programmed cell death protein 1 antibody after several ...[more]