Inflammatory bowel disease and risk of dementia: An updated meta-analysis.

ABSTRACT:

Background

Growing evidence suggests that inflammatory bowel disease (IBD) and dementia share pathological mechanisms and pathogenic risk factors. However, the previously diagnosed IBD and the subsequent risk of developing dementia are largely unknown.

Aim

The purpose of this review is to assess the association between IBD and subsequent dementia diagnosis.

Methods

We searched PubMed, Embase, and Cochrane library from database inception to February 1, 2022. Two reviewers independently extracted data and assessed methodological quality and risk of bias. Observational study that reported the possibility of dementia in IBD and non-IBD populations were included. Eligible studies were pooled effect estimates for relative risk (RR) through fixed-or random-effects models as

SUBMITTER: Liu N 

PROVIDER: S-EPMC9581261 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature