Relation between CarS expression and activation of carotenogenesis by stress in Fusarium fujikuroi.

ABSTRACT: Fusarium fujikuroi, a model organism for secondary metabolism in fungi, produces carotenoids, terpenoid pigments with antioxidant activity. Previous results indicate that carotenoid synthesis in F. fujikuroi is stimulated by light or by different stress conditions and downregulated by a RING finger protein encoded by carS gene. Here, we have analyzed the effects of three stressors, nitrogen scarcity, heat shock, and oxidative stress. We compared them with the effect of light in the wild type, a carS mutant that overproduces carotenoids, and its complemented strain. The assayed stressors increase the synthesis of carotenoids in the three strains, but mRNA levels of structural genes of carotenogenesis, carRA and carB, are only enhanced in the presenc

SUBMITTER: Ruger-Herreros M 

PROVIDER: S-EPMC9581392 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature