Peripheral mononuclear cells composition in platelet-rich fibrin in canines with chronic conditions.

ABSTRACT: Platelet-rich fibrin (PRF) is a hot research topic because of its regenerative effect in humans. However, data reporting about its application in companion animals is lacking. The study aimed to supplement currently available data on PRF cell composition in canine patients by isolating peripheral blood mononuclear cells (PBMC), namely T cells, matured B cells, monocytes and macrophages, and adapting current protocols of cell flow cytometry for PRF analysis. The canine patient population was divided into three subgroups: animals with periodontitis only, animals with neoplasia and periodontitis, and healthy controls. Individual clinical parameters of the patients and evaluation of the wound healing quality were included in the research. In the present study, canine PRF cell composition was a

SUBMITTER: Jasineviciute I 

PROVIDER: S-EPMC9582024 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature