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Dynamic stability of cholesterol and desmosterol in human milk from four Asian countries.


ABSTRACT: Cholesterol is one of the functional nutrients in human milk, which is indispensable for infant growth. In this study, the concentration of cholesterol and desmosterol in human milk from four Asian countries (n = 578), including Korea, China, Vietnam, and Pakistan, were investigated. The average cholesterol concentrations of Korea and China were similar ranging between 90.2-91.6 mg/L, but those from Vietnam and Pakistan were higher at 113.8 and 175.7 mg/L, respectively. The relative standard deviations were 31-36%, except for Pakistan (51%), showing a broad distribution of 48 to 612 mg/L. Desmosterol concentrations were similar, ranging between 11.2 and 12.8 mg/L except for Pakistan, which was lower than other countries at 9.4 mg/L. In addition, the cholesterol and desmosterol concentrations during the lactation periods were not significantly different in all four Asian countries. Mothers' BMI did not significantly impact the cholesterol and desmosterol concentration in maternal milk within the same country.

Supplementary information

The online version contains supplementary material available at 10.1007/s10068-022-01141-9.

SUBMITTER: Kim J 

PROVIDER: S-EPMC9582050 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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Dynamic stability of cholesterol and desmosterol in human milk from four Asian countries.

Kim Jieun J   Nguyen My Tuyen Thi MTT   Kim Yongki Y   Jung Ji A JA   Li Dan D   To Mai Xuan Hong MXH   Nguyen Huynh Khanh Trang HKT   Van Le Thanh T   Israr Beenish B   An Hyun Joo HJ   Kim Jaehan J  

Food science and biotechnology 20220816 12


Cholesterol is one of the functional nutrients in human milk, which is indispensable for infant growth. In this study, the concentration of cholesterol and desmosterol in human milk from four Asian countries (n = 578), including Korea, China, Vietnam, and Pakistan, were investigated. The average cholesterol concentrations of Korea and China were similar ranging between 90.2-91.6 mg/L, but those from Vietnam and Pakistan were higher at 113.8 and 175.7 mg/L, respectively. The relative standard dev  ...[more]

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