Educational attainment polygenic scores, socioeconomic factors, and cortical structure in children and adolescents.

ABSTRACT: Genome-wide polygenic scores for educational attainment (PGS-EA) and socioeconomic factors, which are correlated with each other, have been consistently associated with academic achievement and general cognitive ability in children and adolescents. Yet, the independent associations of PGS-EA and socioeconomic factors with specific underlying factors at the neural and neurocognitive levels are not well understood. The main goals of this study were to examine the unique contributions of PGS-EA and parental education to cortical structure and neurocognitive skills in children and adolescents, and the associations among PGS-EA, cortical structure, and neurocognitive skills. Participants were typically developing 3- to 21-year-olds (53% male; N = 391). High-resolution, T1-weighted magnetic reso

SUBMITTER: Merz EC 

PROVIDER: S-EPMC9582364 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature