Depression in patients with inflammatory bowel disease is associated with increased risk of dementia and Parkinson's disease: A nationwide, population-based study.

ABSTRACT:

Background

Inflammatory bowel disease (IBD) may be associated with depression which is considered an important cause of dementia and Parkinson's disease (PD). In the present study, the effects of depression on the development of dementia and/or PD in patients with IBD were evaluated.

Materials and methods

A nationwide population-based cohort study was conducted using claims data from the Health Insurance Review and Assessment Service in Korea. The incidence of dementia and PD were analyzed based on the presence of depression in patients with IBD.

Results

During a mean follow-up of 8 years, IBD patients with depression experienced dementia (6.7 vs. 2.0%; p < 0.001) and PD (1.1 vs. 0.3%; p < 0.001) significantly more than IBD patients without depression. C

SUBMITTER: Choi K 

PROVIDER: S-EPMC9582438 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature