Health-related quality of life of salvage prostate reirradiation using stereotactic ablative radiotherapy with urethral-sparing.

ABSTRACT:

Purpose

To explore whether prostate motion mitigation using the rectal distension-mediated technique is safe and effective in stereotactic ablative radiation therapy (SABR) salvage treatment of intraprostatic cancer recurrences following initial radiotherapy for primary prostate cancer.

Materials and methods

Between July 2013 and December 2020, 30 patients received salvage SABR for ⁶⁸Ga- PSMA-11 PET/CT-detected intra-prostatic relapses. Median time from primary RT to salvage reirradiation was 70.2 (IQR, 51.3-116.0) months. Median PSA at retreatment was 3.6 ng/mL (IQR, 1.9-6.2). Rectal distension-mediated SABR was achieved with a 150-cm³ air-inflated endorectal balloon and a Foley catheter loaded with 3 beacon transponders was used for urethra visualizat

SUBMITTER: Greco C 

PROVIDER: S-EPMC9582606 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature