Evaluation of the Association of Platelet Count, Mean Platelet Volume, and Platelet Transfusion With Intraventricular Hemorrhage and Death Among Preterm Infants.

ABSTRACT:

Importance

Platelet transfusion is commonly performed in infants to correct severe thrombocytopenia or prevent bleeding. Exploring the associations of platelet transfusion, platelet count (PC), and mean platelet volume (MPV) with intraventricular hemorrhage (IVH) and in-hospital mortality in preterm infants can provide evidence for the establishment of future practices.

Objectives

To evaluate the associations of platelet transfusion, PC, and MPV with IVH and in-hospital mortality and to explore whether platelet transfusion-associated IVH and mortality risks vary with PC and MPV levels at the time of transfusion.

Design, setting, and participants

This retrospective cohort study included preterm infants who were transferred to the neonatal intensive care unit on their d

SUBMITTER: Chen C 

PROVIDER: S-EPMC9582899 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature