Muscle mass and physical function in patients with bladder cancer-Data from a prematurely terminated prospective cohort study.

ABSTRACT:

Background

Patients with bladder cancer (BC) have a high prevalence of comorbidity and low adherence to systemic anticancer treatment but it is unknown whether this is associated with sarcopenia.

Objective

We aimed to investigate if the sarcopenia-defining parameters (muscle strength, muscle mass and physical performance) were associated with reduced adherence to systemic anticancer treatment in patients with BC, and if these muscle domains changed during treatment.

Methods

Patients >18 years of age with BC referred for chemotherapy or immunotherapy at Department of Oncology, Rigshospitalet, Denmark were eligible for study inclusion. Measurements were performed before treatment initiation and within one week after treatment termination, and consisted of assessments of

SUBMITTER: Omland LH 

PROVIDER: S-EPMC9582947 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature