Modeling intracranial electrodes. A simulation platform for the evaluation of localization algorithms.

ABSTRACT:

Introduction

Intracranial electrodes are implanted in patients with drug-resistant epilepsy as part of their pre-surgical evaluation. This allows the investigation of normal and pathological brain functions with excellent spatial and temporal resolution. The spatial resolution relies on methods that precisely localize the implanted electrodes in the cerebral cortex, which is critical for drawing valid inferences about the anatomical localization of brain function. Multiple methods have been developed to localize the electrodes, mainly relying on pre-implantation MRI and post-implantation computer tomography (CT) images. However, they are hard to validate because there is no ground truth data to test them and there is no standard approach to systematically quantify their performance

SUBMITTER: Blenkmann AO 

PROVIDER: S-EPMC9582989 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature