Prevalence of proximate risk factors of active tuberculosis in latent tuberculosis infection: A cross-sectional study from South India.

ABSTRACT: The prevalence of proximate risk factors for active tuberculosis (TB) in areas of high prevalence of latent tuberculosis infection (LTBI) is not clearly understood. We aimed at assessing the prevalence of non-communicable multi-morbidity focusing on diabetes mellitus (DM), malnutrition, and hypertension (HTN) as common risk factors of LTBI progressing to active TB. In a cross-sectional study, 2,351 adults (45% male and 55% female) from villages in the Kancheepuram district of South India were enrolled between 2013 and 2020. DM was defined as HbA1c >6.4%, undernutrition was defined as low body mass index (LBMI) <18.5 kg/m², obesity was classified as BMI ≥25 kg/m², HTN was reported as systolic pressure >130 mmHg, and LTBI was defined as positive (≥ 0.35 international un

SUBMITTER: Munisankar S 

PROVIDER: S-EPMC9583021 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature