Ontology highlight
ABSTRACT:
SUBMITTER: Garrido Ruiz D
PROVIDER: S-EPMC9583617 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Garrido Ruiz Diego D Sandoval-Perez Angelica A Rangarajan Amith Vikram AV Gunderson Emma L EL Jacobson Matthew P MP
Biochemistry 20220926 20
Cysteine side chains can exist in distinct oxidation states depending on the pH and redox potential of the environment, and cysteine oxidation plays important yet complex regulatory roles. Compared with the effects of post-translational modifications such as phosphorylation, the effects of oxidation of cysteine to sulfenic, sulfinic, and sulfonic acid on protein structure and function remain relatively poorly characterized. We present an analysis of the role of cysteine reactivity as a regulator ...[more]