Effects of membrane and flexural stiffnesses on aortic valve dynamics: identifying the mechanics of leaflet flutter in thinner biological tissues.

ABSTRACT: Valvular pathologies that induce deterioration in the aortic valve are a common cause of heart disease among aging populations. Although there are numerous available technologies to treat valvular conditions and replicate normal aortic function by replacing the diseased valve with a bioprosthetic implant, many of these devices face challenges in terms of long-term durability. One such phenomenon that may exacerbate valve deterioration and induce undesirable hemodynamic effects in the aorta is leaflet flutter, which is characterized by oscillatory motion in the biological tissues. While this behavior has been observed for thinner bioprosthetic valves, the specific underlying mechanics that lead to leaflet flutter have not previously been identified. This work proposes a computational approa

SUBMITTER: Johnson EL 

PROVIDER: S-EPMC9583650 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature