Experimental infection of high health pigs with porcine circovirus type 2 (PCV2) and Lawsonia intracellularis.

ABSTRACT:

Background

Porcine circovirus type 2 (PCV2) and Lawsonia intracellularis infections can cause enteritis in pigs. A Danish study showed a significantly higher probability of detecting PCV2 without concurrent L. intracellularis infection, indicating that one of these pathogens has an impact on the dynamics of the other. Therefore, a delayed co-infection model was set up, initially aiming at investigating the interaction between PCV2 and L. intracellularis in pigs challenged with PCV2 and 2 weeks later with L. intracellularis. But due to PCV2 contamination of the L. intracellularis inoculum the aim was revisited to describing the infection dynamics and pathogenesis of pigs infected with PCV2 followed by delayed simultaneous exposure to PCV2 and L.

SUBMITTER: Hansen MS 

PROVIDER: S-EPMC9583870 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature