Chemical Shift-Encoded MRI of Bone Metabolic Markers in Ankylosing Spondylitis.

ABSTRACT:

Objective

To investigate the feasibility and correlation of sacroiliac joint (SIJ) fat fraction (FF) and R2^∗ as markers of bone metabolism in patients with ankylosing spondylitis (AS).

Methods

75 AS patients were classified into an early active group (EA), late active group (LA), and inactive group (IA). Additionally, 54 matched healthy individuals were selected to be part of the normal control group (NC). All participants underwent chemical shift encoded based MRI (IDEAL-IQ) and routine clinical SIJ MRI at 3.0 T. FF and R2^∗ were measured in subchondral bone, bone marrow edema (BME), and fat metaplasia (FM). Out of the participants, 39 with BME lesions (15 from EA, 16 from LA, 8 from IA) and 39 with FM lesions (9 from EA, 17 from LA, 13 from IA) were in

SUBMITTER: Ma LP 

PROVIDER: S-EPMC9584712 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature