The salivary microbiome shows a high prevalence of core bacterial members yet variability across human populations.

ABSTRACT: Human saliva contains diverse bacterial communities, reflecting health status, dietary patterns and contributing to variability in the sensory perception of food. Many descriptions of the diversity of the salivary microbiome have focused on the changes induced by certain diseased states, but the commonalities and differences within healthy saliva have not been fully described. Here, we define and explore the core membership of the human salivary microbial community by collecting and re-analysing raw 16S rRNA amplicon sequencing data from 47 studies with 2206 saliva samples. We found 68 core bacterial taxa that were consistently detected. Differences induced by various host intrinsic and behaviour factors, including gender, age, geographic location, tobacco usage and alcohol consumption wer

SUBMITTER: Ruan X 

PROVIDER: S-EPMC9584946 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature