Changes in the urinary proteome before and after quadrivalent influenza vaccine and COVID-19 vaccination.

ABSTRACT: The proteome of urine samples from quadrivalent influenza vaccine cohort were analyzed with self-contrasted method. Significantly changed urine protein at 24 hours after vaccination was enriched in immune-related pathways, although each person's specific pathways varied. We speculate that this may be because different people have different immunological backgrounds associated with influenza. Then, urine samples were collected from several uninfected SARS-CoV-2 young people before and after the first, second, and third doses of the COVID-19 vaccine. The differential proteins compared between after the second dose (24h) and before the second dose were enriched in pathways involving in multicellular organismal process, regulated exocytosis and immune-related pathways, indicating no first expo

SUBMITTER: Pan X 

PROVIDER: S-EPMC9585259 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature