Mycobacterium genavense Infections in Immunocompromised Patients Without HIV: Case Series of Solid Organ Transplant Patients and Literature Review.

ABSTRACT:

Background

Mycobacterium genavense infection is rare and can occur in immunocompromised patients without human immunodeficiency virus (HIV).

Methods

We describe 2 cases of M genavense infection in solid organ transplant (SOT) recipients, and we performed a literature review of immunocompromised patients without HIV.

Results

Fifty-two cases are reported. Predisposing factors were receipt of SOT (40.4%) and autoimmune disease (36.5%). Infection was disseminated in 86.5% of cases. Organs involved were lymph nodes (72.3%), gastrointestinal tract (56.5%), lung (35.5%), and bone marrow (28.8%). Most patients were treated with at least 3 antimycobacterial agents (98%), with a clinical cure achieved in 54.9%. In multivariate analysis, lack for cure was associate

SUBMITTER: Baldolli A 

PROVIDER: S-EPMC9585469 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature