Whole genome sequencing of Moraxella bovis strains from North America reveals two genotypes with different genetic determinants.

ABSTRACT:

Background

Moraxella bovis and Moraxella bovoculi both associate with infectious bovine keratoconjunctivitis (IBK), an economically significant and painful ocular disease that affects cattle worldwide. There are two genotypes of M. bovoculi (genotypes 1 and 2) that differ in their gene content and potential virulence factors, although neither have been experimentally shown to cause IBK. M. bovis is a causative IBK agent, however, not all strains carry a complete assortment of known virulence factors. The goals of this study were to determine the population structure and depth of M. bovis genomic diversity, and to compare core and accessory genes and predicted outer membrane protein profiles both within and between M. bovis and M. bovoculi.

Results

Phylogenetic trees and bioi

SUBMITTER: Wynn EL 

PROVIDER: S-EPMC9585708 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature