Effects of fentanyl administration in mechanically ventilated patients in the intensive care unit: a systematic review and meta-analysis.

ABSTRACT:

Background

Fentanyl is selected to manage pain in critical care patients on mechanical ventilation in the intensive care unit (ICU). However, the usefulness of fentanyl compared with other opioids is unknown. This study examined the evidence for using fentanyl to improve the clinical outcomes of ICU patients, using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system.

Methods

We searched the MEDLINE, Cochrane Central Register of Controlled Trials, and Igaku Chuo Zasshi databases in June 2021. Two independent assessors reviewed studies to identify randomized, controlled trials (RCTs) that compared the intravenous administration of fentanyl and other opioids in mechanically ventilated patients in the ICU. The study quality was assessed using th

SUBMITTER: Aoki Y 

PROVIDER: S-EPMC9585711 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature