Molecular characteristics of global β-lactamase-producing Enterobacter cloacae by genomic analysis.

ABSTRACT:

Objective

To analyze the characteristics of global β-lactamase-producing Enterobacter cloacae including the distribution of β-lactamase, sequence types (STs) as well as plasmid replicons.

Methods

All the genomes of the E. cloacae were downloaded from GenBank. The distribution of β-lactamase encoding genes were investigated by genome annotation after the genome quality was checked. The STs of these strains were analyzed by multi-locus sequence typing (MLST). The distribution of plasmid replicons was further explored by submitting these genomes to the genome epidemiology center. The isolation information of these strains was extracted by Per program from GenBank.

Results

A total of 272 out of 276 strains were found to carry β-lactamase encoding genes. Among them, 23 var

SUBMITTER: Hu J 

PROVIDER: S-EPMC9585713 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature