The BILAG2004-Pregnancy Index is a valid disease activity outcome measure for pregnant SLE patients.

ABSTRACT:

Objectives

This study was to determine whether the BILAG2004-Pregnancy Index (BILAG2004-P) has construct/criterion validity and is sensitive to change.

Methods

This was an observational multicentre study that recruited pregnant SLE patients. Data were collected on disease activity [using the BILAG2004-P and Physician Global Assessment (PGA)], investigations and therapy at each assessment. The overall BILAG2004-P score as determined by the highest score achieved by any system was used in the analysis. Cross-sectional analysis was used for construct and criterion validity. The comparison was with C3, C4 and anti-dsDNA for construct validity, while it was with change in therapy and PGA in criterion validity. Sensitivity to change was assessed by determining the relationship bet

SUBMITTER: Yee CS 

PROVIDER: S-EPMC9585949 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature