Terrien, a metabolite made by Aspergillus terreus, has activity against Cryptococcus neoformans.

ABSTRACT: Antimicrobial compounds, including antibiotics, have been a cornerstone of modern medicine being able to both treat infections and prevent infections in at-risk people, including those who are immune-compromised and those undergoing routine surgical procedures. Their intense use, including in people, animals, and plants, has led to an increase in the incidence of resistant bacteria and fungi, resulting in a desperate need for novel antimicrobial compounds with new mechanisms of action. Many antimicrobial compounds in current use originate from microbial sources, such as penicillin from the fungus Penicillium chrysogenum (renamed by some as P. rubens). Through a collaboration with Aotearoa New Zealand Crown Research Institute Manaaki Whenua-Landcare Research we have access to

SUBMITTER: Cadelis M 

PROVIDER: S-EPMC9586122 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature