Prevalence of anal dysplasia and HPV genotypes in gynecology patients: The ANGY cross-sectional prospective clinical study protocol.

ABSTRACT:

Background

Human Papillomaviruses (HPV) are highly prevalent in the sexually active populations, with a significant burden in terms of health and psychological cost in all class ages. High-risk (HR) HPV genotypes are associated with anogenital dysplasia and cancers, and anal HPV-induced cancer is increasingly observed in women. The interactions of HPV genotype's between the anus and the cervix, and the subsequent occurrence of dysplasia remains unclear. This clinical study set out to test the hypothesis that risk factors for anal HR-HPV and dysplasia may differ in women with or without cervical dysplasia or in HIV-positive women.

Methods

Cervical and anal HPV genotypes and cytology testing will be performed prospectively in a cohort of women recruited in a tertiary universit

SUBMITTER: Pache B 

PROVIDER: S-EPMC9586359 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature