The value of urinary interleukin-18 in predicting acute kidney injury: a systematic review and meta-analysis.

ABSTRACT:

Aims

The aim of this study was to systematically review relevant studies to evaluate the value of urinary interleukin-18 (uIL-18) in predicting acute kidney injury (AKI).

Methods

A comprehensive search of PubMed, Medline, Embase, and Cochrane Library was conducted for literature published up to 1 August 2022. Quality Assessment Tool for Diagnostic Accuracy Studies-2 (QUADAS-2) was applied to assess the literature quality. Then, relevant data were extracted from each eligible study and a random-effects regression model was utilized to pool sensitivity, specificity, and construct summary receiver operating characteristic (SROC) and area under curve (AUC).

Results

Twenty-six studies with 7183 patients were enrolled and relevant information was extracted. The estimated se

SUBMITTER: Qin Z 

PROVIDER: S-EPMC9586591 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature