Comparison between the Efficacy of Nigella sativa-Honey and Clotrimazole on Vulvovaginal Candidiasis: A Randomized Clinical Trial

ABSTRACT:

Materials and Methods

This triple-blind, randomized controlled trial was conducted on eighty-four 18 to 49-year-old nonpregnant women from August 2019 to February 2020. The subjects were randomly divided into two groups after confirming the diagnosis of VVC infection through fungal culture. Clinical signs and symptoms and lab tests were recorded at baseline and 6–10 days after treatment. The treatment time for each group was seven nights.

Results

There were no significant differences in clinical and laboratory evaluations between the two groups at the beginning of the study (P > 0.05). After treatment, secretion, redness, itching, and fungal culture improved in the two groups (P < 0.001), while pruritus (p = 0.013) and secretion (p = 0.025) in the control group signific

SUBMITTER: Norouzi Allahleh Korabi M 

PROVIDER: S-EPMC9586731 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature