Severe Acute Respiratory Infection-Preparedness: Protocol for a Multicenter Prospective Cohort Study of Viral Respiratory Infections.

ABSTRACT: Respiratory virus infections cause significant morbidity and mortality ranging from mild uncomplicated acute respiratory illness to severe complications, such as acute respiratory distress syndrome, multiple organ failure, and death during epidemics and pandemics. We present a protocol to systematically study patients with severe acute respiratory infection (SARI), including severe acute respiratory syndrome coronavirus 2, due to respiratory viral pathogens to evaluate the natural history, prognostic biomarkers, and characteristics, including hospital stress, associated with clinical outcomes and severity.

Design

Prospective cohort study.

Setting

Multicenter cohort of patients admitted to an acute care ward or ICU from at least 15 hospitals representing diverse geographic reg

SUBMITTER: Postelnicu R 

PROVIDER: S-EPMC9586923 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature