Association between fluid balance and mortality for heart failure and sepsis: a propensity score-matching analysis.

ABSTRACT:

Background

Fluid resuscitation is necessary to correct the sepsis-induced hypoperfusion, which is contradictory to the treatment of heart failure. This study explored the association between fluid balance (FB) of the first 24 h after ICU admission and mortality in critically ill patients with heart failure and sepsis.

Methods

Data were extracted from the Medical Information Mart for Intensive Care database. The locally weighted scatterplot smoothing (Lowess) method was used to demonstrate the relationship between FB and in-hospital mortality. Groups were divided into high FB (≥ 55.85 ml/kg) and low FB (< 55.85 ml/kg) according to the cut-off value of FB using Receiver operating characteristic analysis and Youden index method. The primary outcome was in-hospital mortality. Su

SUBMITTER: Zhang B 

PROVIDER: S-EPMC9587660 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature