A review of trauma and orthopaedic randomised clinical trials published in high-impact general medical journals.

ABSTRACT:

Introduction

The recent past has seen a significant increase in the number of trauma and orthopaedic randomised clinical trials published in "the big five" general medical journals. The quality of this research has, however, not yet been established.

Methods

We therefore set out to critically appraise the quality of available literature over a 10-year period (April 2010-April 2020) through a systematic search of these 5 high-impact general medical journals (JAMA, NEJM, BMJ, Lancet and Annals). A standardised data extraction proforma was utilised to gather information regarding: trial design, sample size calculation, results, study quality and pragmatism. Quality assessment was performed using the Cochrane Risk of Bias 2 tool and the modified Delphi list. Study pragmatism was

SUBMITTER: Farrow L 

PROVIDER: S-EPMC9587938 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature