Ontology highlight
ABSTRACT:
SUBMITTER: Schwarz TM
PROVIDER: S-EPMC9587987 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Schwarz Tim M TM Ott Jonas J Solodenko Helena H Schmitz Guido G Stender Patrick P
Scientific reports 20221022 1
Three-dimensional reconstruction of the analysed volume is one of the main goals of atom probe tomography (APT) and can deliver nearly atomic resolution (~ 0.2 nm spatial resolution) and chemical information with a mass sensitivity down to the ppm range. Extending this technique to frozen biological systems would have an enormous impact on the structural analysis of biomolecules. In previous works, we have shown that it is possible to measure frozen liquids with APT. In this paper, we demonstrat ...[more]