Viral Shedding 1 Year Following First-Episode Genital HSV-1 Infection.

ABSTRACT:

Importance

Herpes simplex virus type 1 (HSV-1) is the leading cause of first-episode genital herpes in many countries.

Objective

To inform counseling messages regarding genital HSV-1 transmission, oral and genital viral shedding patterns among persons with first-episode genital HSV-1 infection were assessed. The trajectory of the development of HSV-specific antibody and T-cell responses was also characterized.

Design, setting, and participants

Prospective cohort followed up for up to 2 years, with 82 participants followed up between 2013 and 2018. Participants were recruited from sexual health and primary care clinics in Seattle, Washington. Persons with laboratory-documented first-episode genital HSV-1 infection, without HIV infection or current pregnancy, were refer

SUBMITTER: Johnston C 

PROVIDER: S-EPMC9588168 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature