Aerobic exercise training and neurocognitive function in cognitively normal older adults: A one-year randomized controlled trial.

ABSTRACT:

Background

Current evidence is inconsistent on the benefits of aerobic exercise training for preventing or attenuating age-related cognitive decline in older adults.

Objective

To investigate the effects of a 1-year progressive, moderate-to-high intensity aerobic exercise intervention on cognitive function, brain volume, and cortical thickness in sedentary but otherwise healthy older adults.

Methods

We randomized 73 older adults to a 1-year aerobic exercise or stretching-and-toning (active control) program. The primary outcome was a cognitive composite score calculated from eight neuropsychological tests encompassing inductive reasoning, long-term and working memory, executive function, and processing speed. Secondary outcomes were brain volume and cortical thickness a

SUBMITTER: Tarumi T 

PROVIDER: S-EPMC9588521 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature