Impact of endorectal filling on interobserver variability of MRI based rectal primary tumor delineation.

ABSTRACT:

Background

Online adaptive MR-guided radiotherapy allows for the reduction of safety margins in dose escalated treatment of rectal tumors. With the use of smaller margins, precise tumor delineation becomes more critical. In the present study we investigated the impact of rectal ultrasound gel filling on interobserver variability in delineation of primary rectal tumor volumes.

Methods

Six patients with locally advanced rectal cancer were scanned on a 1.5 T MRI-Linac without (MRI_e) and with application of 100 cc of ultrasound gel transanally (MRI_f). Eight international radiation oncologists expert in the treatment of gastrointestinal cancers delineated the gross tumor volume (GTV) on both MRI scans. MRI_f scans were provided to the participating centers after MRI_e scans had

SUBMITTER: Lo Russo M 

PROVIDER: S-EPMC9589000 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature