Use of connectotyping on task functional MRI data reveals dynamic network level cross talking during task performance.

ABSTRACT: Task-based functional MRI (fMRI) has greatly improved understanding of brain functioning, enabling the identification of brain areas associated with specific cognitive operations. Traditional analyses are limited to associating activation patterns in particular regions with specific cognitive operation, largely ignoring regional cross-talk or dynamic connectivity, which we propose is crucial for characterization of brain function in the context of task fMRI. We use connectotyping, which efficiently models functional brain connectivity to reveal the progression of temporal brain connectivity patterns in task fMRI. Connectotyping was employed on data from twenty-four participants (12 male, mean age 24.8 years, 2.57 std. dev) who performed a widely spaced event-related fMRI word vs. pseudowor

SUBMITTER: Vazquez-Trejo V 

PROVIDER: S-EPMC9589037 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature