The prevalence of thyroid dysfunction and autoimmune thyroid disease in patients with rheumatoid arthritis.

ABSTRACT:

Background

Rheumatoid arthritis (RA) is one of the most common chronic non-organ-specific autoimmune diseases; meanwhile, autoimmune thyroid disease (AITD) is the most common organ-specific autoimmune disease that can lead to hypo or hyperthyroidism. Although the etiology of both diseases is complex with a combination of genetic and environmental factors, there are overlaps in genes contributing to the pathogenesis of both diseases. Numerous studies found a correlation between thyroid abnormality and RA in different populations, yet some didn't. This study is aimed to evaluate the prevalence of thyroid dysfunction, AITD, and anti-thyroid peroxidase (anti-TPO) positively in Iranian patients with RA.

Methods

A total of 250 RA patients and 248 patients with non-inflammatory rhe

SUBMITTER: Bagherzadeh-Fard M 

PROVIDER: S-EPMC9590164 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature