Sex-specific changes in triglyceride profiles in liver cirrhosis and hepatitis C virus infection.

ABSTRACT:

Background

Hepatitis C virus (HCV) infection is associated with serum lipid abnormalities, which partly normalize following direct-acting antiviral (DAA) therapy. Here, associations of serum triglycerides (TGs) with viral genotype and markers of liver disease severity were evaluated in patients with chronic HCV.  METHODS: The study included the serum of 177 patients with chronic HCV. TGs were quantified by flow injection analysis Fourier transform mass spectrometry. Laboratory values and noninvasive scores for liver fibrosis assessment were determined. The nonparametric Kruskal‒Wallis test, one-way ANOVA, multiple linear regression and Student's t test were used as appropriate. P values were adjusted for multiple comparisons.

Results

HCV-infected women had lower serum TGs th

SUBMITTER: Peschel G 

PROVIDER: S-EPMC9590217 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature