Transcriptome-wide N⁶-methyladenosine (m⁶A) methylation in soybean under <i>Meloidogyne incognita</i> infection.

ABSTRACT: N⁶-methyladenosine (m⁶A) is a reversible epigenetic modification of mRNA and other RNAs that plays a significant role in regulating gene expression and biological processes. However, m⁶A abundance, dynamics, and transcriptional regulatory mechanisms remain unexplored in the context of soybean resistance to Meloidogyne incognita. In this study, we performed a comparative analysis of transcriptome-wide m⁶A and metabolome profiles of soybean root tissues with and without M. incognita infection. Global m⁶A hypermethylation was widely induced in response to M. incognita infection and was enriched around the 3' end of coding sequences and in 3' UTR regions. There were 2069 significantly modified m⁶A sites, 594

SUBMITTER: Han X 

PROVIDER: S-EPMC9590533 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature