A novel ferroptosis‑related gene signature for overall survival prediction and immune infiltration in patients with breast cancer.

ABSTRACT: Breast cancer is the most prevalent type of cancer among women worldwide. The heterogeneous nature of breast cancer poses a serious challenge for prognostic prediction and individualized therapies. Recently, ferroptosis, an iron‑dependent form of programmed cell death, has been reported to serve a significant role in the regulation of the biological behavior of tumors. Several studies have revealed the prognostic significance of the ferroptosis‑related gene (FRG) model; however, additional efforts are required to elucidate the details. Moreover, genes that modulate ferroptosis may be promising candidate bioindicators in cancer therapy. The present study systematically assessed the expression profiles of FRGs to reveal the relationship between FRGs and the prognostic features of patients wi

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9591322 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature