50% effective concentration of sevoflurane for immobility in cerebral palsy children undergoing botulinum toxin injection.

ABSTRACT:

Background

This prospective study aimed to determine the optimum end-tidal sevoflurane concentration required for immobility during botulinum toxin injection in spontaneously breathing children with cerebral palsy (CP).

Methods

Twenty-three children with spastic CP, aged 3 to 12 years, with American Society of Anesthesiologists (ASA) physical status I and II, scheduled to receive botulinum toxin type A injection were enrolled in the study. After induction of deep sedation using pre-filled 8% sevoflurane in oxygen and maintenance of the predetermined end-tidal sevoflurane concentration, the botulinum toxin was injected in spontaneously breathing children. The response to the botulinum toxin injection was classified as "movement" or "no movement" by an independent investigator

SUBMITTER: Kim K 

PROVIDER: S-EPMC9592399 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature