Alcohol use and cognitive aging in middle-aged men: The Vietnam Era Twin Study of Aging.

ABSTRACT:

Objective

To determine associations of alcohol use with cognitive aging among middle-aged men.

Method

1,608 male twins (mean 57 years at baseline) participated in up to three visits over 12 years, from 2003-2007 to 2016-2019. Participants were classified into six groups based on current and past self-reported alcohol use: lifetime abstainers, former drinkers, very light (1-4 drinks in past 14 days), light (5-14 drinks), moderate (15-28 drinks), and at-risk drinkers (>28 drinks in past 14 days). Linear mixed-effects regressions modeled cognitive trajectories by alcohol group, with time-based models evaluating rate of decline as a function of baseline alcohol use, and age-based models evaluating age-related differences in performance by current alcohol use. Analyses used stand

SUBMITTER: Garduno AC 

PROVIDER: S-EPMC9592679 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature