Insights from the genome sequence of Bacillus tropicus EMB20, an efficient β-lactamase-producing bacterium.

ABSTRACT: We report here the whole-genome sequence of β-lactamase-producing bacteria Bacillus tropicus EMB20. The genome sequence of Bacillus tropicus EMB20 has a size of 5.8 Mb (G + C content of 35.52%) with 5593 coding DNA sequences (CDSs), 108 tRNA, and 14 rRNA operons. The bacterium has the unique ability to produce a β-lactamase enzyme with high activity. β-Lactamases are one of the most common causes of antimicrobial resistance as these enzymes inactivate almost all β-lactam antibiotics. The antibiotic susceptibility test showed that the B. tropicus EMB20 is producing β-lactamase and can degrade the β-lactam antibiotics. Further, the antibiotic degradation potential of this bacteria was confirmed by growing the bacteria in the presence of varying concentrations of β

SUBMITTER: Fatima H 

PROVIDER: S-EPMC9592686 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature