Clinical carbapenem-resistant Klebsiella pneumoniae isolates simultaneously harboring bla _NDM-1, bla _OXA types and qnrS genes from the Kingdom of Bahrain: Resistance profile and genetic environment.

ABSTRACT: The prevalence of Carbapenem-resistant Klebsiella pneumoniae (CRKP) is currently increasing worldwide, prompting WHO to classify it as an urgent public health threat. CRKP is considered a difficult to treat organism owing to limited therapeutic options. In this study, a total of 24 CRKP clinical isolates were randomly collected from Salmaniya Medical Complex, Bahrain. Bacterial identification and antibiotic susceptibility testing were performed, on MALDI-TOF and VITEK-2 compact, respectively. The isolates were screened for carbapenem resistance markers (bla _NDM, bla _OXA-23, bla _OXA-48 and bla _OXA-51) and plasmid-mediated quinolone resistance genes (qnrA, qnrB, and qnrS) by monoplex PCR. On the othe

SUBMITTER: Shahid M 

PROVIDER: S-EPMC9592905 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature