The value of plasma insulin-like growth factor 1 and interleukin-18 in the diagnosis of bronchopulmonary dysplasia in premature infants

ABSTRACT:

Objective

To explore the diagnostic value of IGF-1 and IL-18 in premature infants with BPD.

Methods

Through a prospective observational study, the serum samples of infants in the BPD group and the non-BPD group were collected at different targeted time points, and the serum IGF-1 and IL-18 concentrations were dynamically monitored by ELISA. The Student t-test and one-way analysis of variance were adopted to analyze data, and the receiver operating characteristic (ROC) curve was used to test the diagnostic value.

Result

A total of 90 VLBW premature infants admitted to NICU between January 2020 and 2021 were finally included. Compared with the non-BPD group, infants diagnosed with BPD had a significantly lower serum concentration of IGF-1 (P < 0.05) but a higher le

SUBMITTER: Huang L 

PROVIDER: S-EPMC9592911 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature