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Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life.


ABSTRACT: We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of future norovirus vaccines.

SUBMITTER: Vielot NA 

PROVIDER: S-EPMC9595050 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life.

Vielot Nadja A NA   Brinkman Amanda A   DeMaso Christina C   Vilchez Samuel S   Lindesmith Lisa C LC   Bucardo Filemon F   Reyes Yaoska Y   Baric Ralph S RS   Ryan Elizabeth P EP   Braun Ralph R   Becker-Dreps Sylvia S  

Journal of the Pediatric Infectious Diseases Society 20221001 10


We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of future norovirus vaccines. ...[more]

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