Post-diagnostic health behaviour scores in relation to fatal prostate cancer.

ABSTRACT:

Background

Individual health behaviours have been associated with fatal prostate cancer (PCa). Their combined association with fatal PCa after diagnosis is unknown.

Methods

This prospective cohort included 4518 men diagnosed with nonmetastatic PCa from the Health Professionals Follow-up Study. Exposures included a three-factor score integrating post-diagnostic fatal PCa risk factors ("2021 PCa Behaviour Score"), six-factor score integrating incident aggressive PCa risk factors ("2015 PCa Behaviour Score"), and two scores integrating recommendations for cancer prevention and survival, respectively. Multivariable Cox models estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for fatal PCa.

Results

Over a median 10.2 years, we observed 219 PCa deaths. Each a

SUBMITTER: Graff RE 

PROVIDER: S-EPMC9596495 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature