Soy product intake and risk of incident disabling dementia: the JPHC Disabling Dementia Study.

ABSTRACT:

Purpose

We evaluated the association between total soy, soy product (natto, miso and tofu) and isoflavone intake and incident disabling dementia in a Japanese population.

Methods

We conducted a population-based prospective study in 18,991 men and 22,456 women. Intake of soy products and isoflavone was calculated using a validated food frequency questionnaire when participants were 45-74 years old (1995 and 1998). Incident disabling dementia was defined by the daily living disability status related to dementia in the long-term care insurance program of Japan from 2006 to 2016. Multivariate hazard ratios (HRs) and 95% confidence intervals (CIs) of disabling dementia were calculated by quintiles of total soy, individual soy product and isoflavone intake, using Cox proportional

SUBMITTER: Murai U 

PROVIDER: S-EPMC9596534 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature