Gating by Memory: a Theory of Learning in the Cerebellum.

ABSTRACT: This paper presents a model of learning by the cerebellar circuit. In the traditional and dominant learning model, training teaches finely graded parallel fibre synaptic weights which modify transmission to Purkinje cells and to interneurons that inhibit Purkinje cells. Following training, input in a learned pattern drives a training-modified response. The function is that the naive response to input rates is displaced by a learned one, trained under external supervision. In the proposed model, there is no weight-controlled graduated balance of excitation and inhibition of Purkinje cells. Instead, the balance has two functional states-a switch-at synaptic, whole cell and microzone level. The paper is in two parts. The first is a detailed physiological argument for the synaptic learning fun

SUBMITTER: Gilbert M 

PROVIDER: S-EPMC9596590 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature